Hantzsch 1, 4-dihydropyridines ( Hantzsch 1,4-DHP) attract great interest for their importance in organic synthesis and biochemistry. 1,4-二氢吡啶类化合物作为一类具有重要生物活性的化合物,引起了人们极大的兴趣。
Methods Amlodipine besylate were designed and synthesized from ethanolamine and phthalic anhydride via condensation, Hantzsch synthesis, reduction, and salt formation. 方法自行设计苯磺酸氨氯地平的合成路线,以氨基乙醇和邻苯二甲酸酐为起始原料,经缩合、Hantzsch合成、还原、成盐反应得到目标化合物。
A further application of Hantzsch ester as an organic reducing agent was well performed in the synthesis of 3,4-dihydrocoumarin via microwave irradiation. 微波反应中汉斯酯作为有机还原剂在合成3,4-二氢香豆素中的应用研究。